4,4-difluoropiperidine-1-formic acid tert-butyl ester
tert-butyl 4,4-difluoropiperidine-1-carboxylate
CAS: 281652-10-6
Molecular Formula: C10H17F2NO2
4,4-difluoropiperidine-1-formic acid tert-butyl ester - Names and Identifiers
4,4-difluoropiperidine-1-formic acid tert-butyl ester - Physico-chemical Properties
| Molecular Formula | C10H17F2NO2 |
| Molar Mass | 221.24 |
| Density | 1.12±0.1 g/cm3(Predicted) |
| Boling Point | 247.7±40.0 °C(Predicted) |
| pKa | -4.70±0.40(Predicted) |
| Storage Condition | 2-8°C |
4,4-difluoropiperidine-1-formic acid tert-butyl ester - Introduction
tert-butyl 4 is an organic compound with the chemical formula C10H16F2NO2. It is a colorless liquid with a density of 1.109g/cm³ at normal temperature and pressure. It is soluble in organic solvents such as ether and toluene, and insoluble in water.
This compound can be used in organic synthesis reactions as a synthetic intermediate. It can be hydrogenated to 4,4-difluoropiperidine-L-carboxylic acid tert-butyramide, and then through other reactions to prepare the target compound. It can also be used as a raw material for drug development and pesticide synthesis.
The method for preparing tert-butyl 4 can be obtained by reacting fluoroacetic acid and tert-butyl alcohol as raw materials. First, fluoroacetic acid is added to tert-butyl alcohol, and then the esterification reaction is carried out under the catalysis of alkali to produce tert-butyl 4, phosphors.
Regarding the safety information of this substance, it has irritating and corrosive effects on the skin and eyes. After contact with the skin or eyes, rinse with plenty of water immediately and seek medical help. During use, care should be taken to avoid inhaling its vapor or dust and maintain good ventilation conditions.
This compound can be used in organic synthesis reactions as a synthetic intermediate. It can be hydrogenated to 4,4-difluoropiperidine-L-carboxylic acid tert-butyramide, and then through other reactions to prepare the target compound. It can also be used as a raw material for drug development and pesticide synthesis.
The method for preparing tert-butyl 4 can be obtained by reacting fluoroacetic acid and tert-butyl alcohol as raw materials. First, fluoroacetic acid is added to tert-butyl alcohol, and then the esterification reaction is carried out under the catalysis of alkali to produce tert-butyl 4, phosphors.
Regarding the safety information of this substance, it has irritating and corrosive effects on the skin and eyes. After contact with the skin or eyes, rinse with plenty of water immediately and seek medical help. During use, care should be taken to avoid inhaling its vapor or dust and maintain good ventilation conditions.
Last Update：2024-04-09 15:17:56
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View History
4,4-difluoropiperidine-1-formic acid tert-butyl ester
Loratadine Impurity 39
(2R,3R)-2-(Fmoc-氨基)-3-叔丁氧基-1-丁醇
102584-05-4
内南五味子酯C
ILE-PRO-GLN-SER-LEU-ASP-SER-TRP-TRP-THR-SER-LEU
Bicyclo[3.1.1]heptane-2,3-diol, 2,6,6-trimethyl-, (1S,2S,3S,5S)-
N-(2-METHOXY-5-NITROPHENYL)-2-(4-METHYLPIPERAZINO)ACETAMIDE
聚(4-甲基-1-戊烯),中分子量
3-(4-ethylphenyl)-8-azabicyclo[3.2.1]oct-2-ene hydrochloride
Loratadine Impurity 39
(2R,3R)-2-(Fmoc-氨基)-3-叔丁氧基-1-丁醇
102584-05-4
内南五味子酯C
ILE-PRO-GLN-SER-LEU-ASP-SER-TRP-TRP-THR-SER-LEU
Bicyclo[3.1.1]heptane-2,3-diol, 2,6,6-trimethyl-, (1S,2S,3S,5S)-
N-(2-METHOXY-5-NITROPHENYL)-2-(4-METHYLPIPERAZINO)ACETAMIDE
聚(4-甲基-1-戊烯),中分子量
3-(4-ethylphenyl)-8-azabicyclo[3.2.1]oct-2-ene hydrochloride